Applied LC and LC-MS method development and advanced techniques
- Duration: 1 day for face-to-face
- Experience level: Advanced
- Delivery methods: Face-to-face | Offsite training & consultancy | On-Demand | Online | Onsite training & consultancy | Tailored training |
- Manufacturer(s):
- CPD Approved: Not yet approved
- Scheduled course price: £385.00 + TAX per delegate
- Course discounts: RSC CAMS Heated members receive a discount on this course
What will you learn on this course?
Day 4 / Modules 9 – 10 of the Complete HPLC & LC-MS course and Day 1 of The HPLC & LC-MS Clinic course.
First, the course examines the method development process in detail; covering the objectives of the analytical method, how many components are to be separated and the required sensitivity, selectivity, specificity and the speed of analysis. This is followed by system optimisation and configuration for LC and LC-MS. All of this knowledge is then put to the test in case studies.
The course then looks at method validation protocols, system suitability and outlines the steps required for analytical method accreditation.
The last part of the day covers a brief introduction to some advanced techniques that can be used for difficult or complex samples including detector selectivity and specificity, UHPLC vs. HPLC (brief introduction to method transfer), chromatographic peak deconvolution using tandem mass spectrometry, multi-dimensional LC (LCxLC), on-line SPE and chemometrics.
Combine other days or modules.Learning outcomes
- You will learn strategies for HPLC & LC-MS method development.
- You will learn about system optimisation and configuration for HPLC and LC-MS.
- You will get an introduction to advanced HPLC & LC-MS techniques.
Who is this course for?
Before attending this one day course you should have a good knowledge of liquid chromatography and the techniques covered in days 1-3 / modules 1 – 8.
