The second edition of the Chiral Handbook provides nearly 400 pages of information related to chiral separations. Sections include HPLC and SFC Method Development Guides, frequently asked questions, and column selection advice. One of the biggest challenges is finding the best column for separating compounds of various types, as there is no universal chiral stationary phase, and predicting which chiral stationary phase will provide the best separation is difficult. Look to the Handbook for best practices or use Regis’s screening service for a confidential and complimentary separation method for any chiral compound. The book contains over 950 chiral applications using a variety of column types.