Applied LC and LC-MS maintenance
- Duration: 2.50 hours for on-demand
- Experience level: Intermediate
- Delivery methods: Offsite training & consultancy | On-Demand | Online | Onsite training & consultancy | Tailored training |
- Type of course: Universal
- Applicable to manufacturer(s): Agilent | Bruker | CTC analytics | JASCO | PerkinElmer | Sciex | Scion | Shimadzu | Thermo | Waters |
- CPD Approved: Approved
- Scheduled course price: £162.50 + TAX per delegate
- Course discounts: RSC CAMS HEaTED Cambridge Network members receive a discount on this course
Your applied guide to liquid chromatography (LC) and liquid chromatography-mass spectrometry (LC-MS) maintenance
Module 11 of the Complete LC and LC-MS course and module 3 of The LC and LC-MS Clinic course.
Applied LC and LC-MS maintenance is approved by the Royal Society of Chemistry (RSC) for the purposes of Continuing Professional Development (CPD). Designed for professionals, students and chemists, this module explores the essential maintenance procedures required to maximise performance, reliability and uptime of LC and LC-MS systems. As well as covering preventative maintenance, troubleshooting, column care, vacuum systems, ion source cleaning, and routine performance checks to help you maintain instruments in peak operating condition.
This module can be combined with any of the other twelve modules in the Complete LC and LC-MS to tailor your training needs.
Why should I join?
On completion of this module 11 training, you will gain an understanding of maintenance strategies and requirements for LC and LC-MS, giving you:
- An overview of preventative maintenance practices for LC and LC-MS systems
- Understanding of how proper maintenance improves instrument reliability and data quality
- Insight into common sources of contamination and how to minimise them
- Practical guidance on maintaining columns, pumps, detectors, and autosamplers
- Knowledge of routine maintenance requirements for LC-MS vacuum and ionisation systems
- Understanding of performance monitoring and preventative maintenance schedules
What would I learn?
This module focuses on the maintenance and care of LC and LC-MS instrumentation, you will learn:
- How to implement effective preventative maintenance procedures for LC and LC-MS systems
- Best practice for mobile phase preparation, contamination control, and solvent management
- How to protect, store, regenerate and troubleshoot chromatographic columns
- The maintenance requirements of injectors, pumps, autosamplers, and detectors
- How to perform preventative maintenance checks and benchmark system performance
- The principles of LC-MS vacuum system maintenance, including rotary and scroll pumps
- How to clean and maintain ion sources, sample cones, and ion transfer optics
What knowledge will I gain?
By the end of the module, you will:
- Understand how routine maintenance contributes to data quality, reliability, and instrument uptime
- Know how to identify common causes of poor chromatographic performance and instrument contamination
- Understand the maintenance requirements of major LC system components
- Know how to establish effective preventative maintenance schedules for LC and LC-MS systems
- Understand the operation and maintenance of LC-MS vacuum systems and gas supplies
- Know how to recognise indicators of ion source contamination and declining mass spectrometer performance
- Understand the importance of pre- and post-maintenance performance verification
- Gain confidence in maintaining LC and LC-MS systems to maximise performance and minimise downtime
Is this course for me?
This course is designed for anyone who would like to improve their understanding of LC and LC-MS maintenance and instrument care.
- Laboratory analysts and technicians responsible for the day-to-day operation of LC and LC-MS systems
- Laboratory managers responsible for instrument performance and laboratory productivity
- Service engineers seeking a deeper understanding of LC and LC-MS maintenance procedures
- Scientists responsible for troubleshooting and maintaining analytical instrumentation
- Sales, commercial and marketing teams supporting chromatography and mass spectrometry products and services
If LC and LC-MS touches your work in any way, this practical course delivered by experts in the field will equip you with the knowledge required to understand these techniques.
Select the courses you are interested in:
Feedback from previous attendees
“Useful, give good tips on how to help keep instruments in check.” Mollie Nero, Project Scientist, Broughton Nicotine Services (February 2021).
“This was a very useful module as it provided a link between the large amount of theory we had learnt and actual real world problems that we may have at work.” Joe Richardson, Assistant Scientist, Environment Agency (November 2020).
