Hands-on GC-MS theory and methods
- Duration: 1 day for live courses
- Experience level: Intermediate
- Delivery methods: Face-to-face | Offsite training & consultancy | Onsite training & consultancy | Tailored training |
- Type of course: Universal
- Applicable to manufacturer(s): Agilent | Bruker | Leco | PerkinElmer | Scion | Shimadzu | SRI | Thermo | Varian | Waters |
- CPD Approved: Approved
- Scheduled course price: £650.00 + TAX per delegate
- Course discounts: RSC CAMS HEaTED Cambridge Network members receive a discount on this course
Your Hands-on approach to learning gas chromatography-mass spectrometry (GC-MS) theory and methods
Day 3 of our Hands-on GC and GC-MS
Combine the practical theory of GC-MS with laboratory-based exercises in this Royal Society of Chemistry (RSC) approved training for the purposes of Continued Professional Development (CPD). This course is designed to bridge the gap between theory and practice, enabling you to confidently use GC-MS instrumentation within the laboratory.
This Hands-on course is ideal for students, analysts and professionals who want to gain practical experience with all aspects of GC-MS including mass analysers, vacuum systems, data acquisition, qualitative identification and quantitative analysis. Learn how gas chromatography and mass spectrometry are combined to provide both chromatographic separation and molecular identification, while developing the practical skills needed to create methods, acquire data and interpret results.
Why should I join?
On completion, you will have both the theoretical knowledge and practical experience required to confidently operate and optimise GC-MS systems in your laboratory.
This Hands-on GC-MS theory and methods course gives you:
- Strong theoretical and practical skills for using GC-MS instrumentation
- Practical guidance on ionisation techniques, mass analysers and detector systems
- Hands-on experience creating and optimising GC-MS methods
- An understanding of qualitative and quantitative GC-MS workflows
- Practical experience working with scan, SIM and MS/MS acquisition modes
- Confidence interpreting chromatograms, mass spectra and library search results
- A structured approach to selecting suitable GC-MS technologies for different applications
What would I learn?
A user-friendly GC-MS course that combines in-depth theory with practical laboratory exercises, you will learn:
- The principles of mass spectrometry and how GC and MS are hyphenated together
- How vacuum systems and GC-MS interfaces operate
- The principles of electron ionisation (EI), positive chemical ionisation (PCI) and negative chemical ionisation (NCI)
- How ions are generated, separated and detected within a mass spectrometer
- The operation and applications of quadrupole, ion trap, time-of-flight, Orbitrap and triple quadrupole analysers
- How acquisition parameters influence sensitivity, selectivity and data quality
- The principles of GC-MS method development and optimisation
- How to perform qualitative identification using mass spectra and library searching
- How to perform quantitative analysis using GC-MS data
What knowledge will I gain?
- Understand the complete GC-MS analytical workflow from chromatographic separation through to molecular identification and quantitation
- Understand how ionisation techniques influence fragmentation patterns and spectral information
- Explain the strengths and limitations of different mass analyser technologies
- Understand the relationship between acquisition speed, sensitivity, mass range and mass resolution
- Recognise the importance of vacuum integrity, carrier gas quality and contamination control
- Interpret mass spectra, extracted ion chromatograms and total ion chromatograms
- Understand the principles and limitations of library searching and unknown identification
- Diagnose common data quality issues including background interference and spectral skewing
- Select appropriate acquisition modes and analytical strategies for different GC-MS applications
Is this course for me?
This RSC approved for purposes of CPD training is designed for anyone who needs both a theoretical and practical understanding of GC-MS, including:
- Analysts & technicians requiring training or a clear structured refresher of GC and GC-MS
- Laboratory or line managers overseeing GC and GC-MS instrumentation
- Data analysts and report writers who interpret results but don’t use the instruments
- Service and consultant engineers who need both a theoretical and a hands-on reminder
- Sales, marketing or commercial teams working with GC and GC-MS systems, consumables, data or laboratory services
If GC and GC-MS touches your work in any way, this well-planned course delivered by experts in the field equips you to understand the science behind these techniques.
Course combinations
Can’t attend the full course? No worries, combine days or modules to create training that works best for you. The more days you book the larger the discount.
- For 2 days, pay £1250
- For 3 days, pay £1825
- For 4 days, pay £2350
- For 5 days, pay £2850
Please note, discounts won’t apply when booking but will appear on your invoice.
