The GC and GC-MS Clinic
- Duration: 2 days for live courses 13 hours for on-demand
- Experience level: Intermediate
- Delivery methods: Face-to-face | Offsite training & consultancy | On-Demand | Online | Onsite training & consultancy | Tailored training |
- Type of course: Universal
- Applicable to manufacturer(s): Agilent | Bruker | CDS Analytical | CTC analytics | Frontier | GERSTEL | GL Sciences | Leco | OI Analytical | PerkinElmer | Scion | Shimadzu | SRI | Thermo | Varian | Waters |
- CPD Approved: Approved
- Scheduled course price: £825.00 + TAX per delegate
- Course discounts: RSC CAMS HEaTED Cambridge Network members receive a discount on this course
Your advanced troubleshooting, optimisation and problem-solving training for experienced gas chromatography (GC) and GC-mass spectrometry (GC-MS) users
Day 4 and 5 of the Complete GC and GC-MS.
The GC & GC-MS Clinic is a Royal Society of Chemistry (RSC) approved for the purposes of Continuing Professional Development (CPD) course designed for professionals, students and chemists who are experienced chromatographers seeking to enhance their ability to troubleshoot complex analytical problems, optimise method performance, and apply advanced chromatographic and mass spectrometric techniques. This course focuses on the challenges encountered when routine approaches are no longer sufficient and a deeper understanding of the science is required. Based on GC and GC-MS method development, advanced techniques and maintenance and troubleshooting, you will gain the skills needed to diagnose difficult problems, improve method performance, and maximise the information obtained from GC and GC-MS systems.
Whether you are working with complex matrices, trace-level compounds, co-eluting peaks, difficult identifications, or demanding regulatory requirements, this course provides advanced strategies to help you achieve better analytical outcomes.
Why should I join?
This course provides a structured approach to method development, advanced techniques and why problems occur, plus how to solve them efficiently whilst improving method performance, giving you:
- A systematic approach to solving complex chromatographic and mass spectrometric problems
- Advanced understanding of method optimisation and performance improvement strategies
- Insight into the causes of poor sensitivity, selectivity, resolution, and reproducibility
- Knowledge of advanced GC and GC-MS techniques used to overcome challenging analytical problems
- Practical guidance on dealing with co-elution, difficult matrices, trace-level analytes, and unknown compounds
- Understanding of how every stage of the analytical workflow contributes to overall method performance
- A valuable opportunity to develop higher-level troubleshooting and decision-making skills
What would I learn?
This course focuses on advanced troubleshooting, optimisation, and analytical problem solving, you will learn:
- How to systematically investigate and diagnose challenging GC and GC-MS problems
- How sampling, sample preparation, injection, separation, detection, and data processing contribute to analytical performance
- Advanced strategies for improving chromatographic resolution and sensitivity
- How to optimise column selection, carrier gas conditions, temperature programmes, and detector settings
- How to troubleshoot difficult analytes including thermally labile, active, trace-level, and high molecular weight compounds
- The principles of advanced mass spectral interpretation and structural elucidation
- Techniques for resolving co-eluting peaks using deconvolution and advanced data processing approaches
- How selective discrimination techniques can reduce matrix interferences and improve sensitivity
- The principles and applications of fast GC, heart-cutting GC, multidimensional GC, and comprehensive two-dimensional GC (GC×GC)
- Practical approaches to method refinement, performance evaluation, and validation
What knowledge will I gain?
By the end of the course, you will:
- Understand how to take a systematic approach to complex analytical investigations
- Be able to identify root causes of chromatographic and mass spectrometric problems more efficiently
- Understand how advanced optimisation strategies influence sensitivity, selectivity, accuracy, and robustness
- Learn how advanced GC-MS techniques can improve identification confidence and quantitative performance
- Be able to evaluate when advanced techniques such as deconvolution, GC×GC, or selective discrimination are appropriate
- Understand how to improve performance in challenging applications involving complex sample matrices
- Gain confidence in interpreting mass spectra and compound identification data
- Understand how to critically evaluate existing methods and identify opportunities for improvement
- Develop the expertise required to solve challenging GC and GC-MS analytical problems
Is this course for me?
This RSC approved for CPD GC and GC-MS training designed for anyone who would like advanced knowledge on both techniques.
- Laboratory analysts & technicians using GC and GC-MS
- Laboratory or line managers overseeing GC and GC-MS instruments and analysis
- Data analysts and report writers who work with GC and GC-MS
- Service engineers who want chemistry focused introduction to GC and GC-MS
- Sales, commercial or marketing teams who work with GC and GC-MS components, instruments, or services in anyway and would like more in-depth knowledge
If GC and GC-MS touches your work in any way, this well-planned course delivered by experts in the field equips you to understand the science behind these techniques.
