Absolute Basics of MALDI-TOFMS
- Duration: 1 day for live courses 6.50 hours for on-demand
- Experience level: Beginners
- Delivery methods: On-Demand |
- Type of course: Universal
- Applicable to manufacturer(s):
- CPD Approved: Not yet approved
- Scheduled course price: £385.00 + TAX per delegate
- Course discounts: RSC CAMS HEaTED members receive a discount on this course
Your beginner’s guide to matrix-assisted laser desorption ionisation time-of-flight mass spectrometry (MALDI-TOFMS)
Learn the fundamentals of matrix-assisted laser desorption ionisation (MALDI) and time-of-flight mass spectrometry (TOFMS), with this 1-day classroom-based beginners course for professionals and students. This introductory, analytical chemistry course will cover the what, how, why, where and when of MALDI-TOFMS and will take you from the importance of sample preparation through to laser ionisation of the sample and detection of the analyte via TOF-MS.
Whether you are stepping into the world of MALDI-TOFMS for the first time, or looking to refresh your technical expertise, this essential training course gives you the knowledge to understand and use MALDI-TOFMS as an analytical tool to measure the mass and determine the identity of large molecules. This course breaks complex MALDI-TOFMS instrumentation and techniques into easy-to-understand concepts, helping you build skills that you can use in the lab.
Why should I join Absolute Basics of MALDI-TOFMS?
On completion, you will be able to understand what defines MALDI-TOFMS, its typical applications and uses in analytical chemistry and the life sciences, as well as sample preparation and the fundamental concepts behind using MALDI-TOFMS.
This MALDI-TOFMS training course gives you:
- A solid understanding of MALDI-TOFMS theory, the ionisation and detection processes
- Clear explanations of MALDI-TOFMS instrumentation and the data it provides
- Insight into different MALDI spectrometers and the TOF mass analyser
- Understanding a MALDI-TOFMS spectrum and the information it provides
- Familiarity with matrix concepts including silent matrices, liquid and ionic liquid matrices
- Knowledge of the benefits of using MALDI-TOFMS as an analytical technique
- Real-life applications of MALDI-TOFMS in areas such as nanomaterials, proteomics and organometallic compound analysis
- Interactive exercises of example applications across different industries
- A great summary of MALDI-TOFMS aided with an acronym glossary
This is your opportunity to understand MALDI-TOFMS, and how it is used in everyday analytical science life.
What would I learn on Absolute Basics of MALDI-TOFMS?
A beginner‑friendly introductory course focusing on the what, how, why, where and when of MALDI-TOFMS, including:
- What MALDI-TOFMS is
- What defines both MALDI and TOF-MS and the common terminology used
- What defines isotope patterns, mass spectra and mass calibration
- What mass spectrometry is and its components
- How MALDI-TOFMS works
- The core principles behind MALDI-TOFMS from laser desorption to detection via TOF-MS
- How additives can be used to aid the ionisation process
- How different sample preparation types such as dried-droplet deposition and fast evaporation are used in MALDI TOFMS
- Why we use MALDI-TOFMS
- Why MALDI-TOFMS is used for a wide variety of analytes
- Why matrix and laser power should ensure simple spectra
- Why the technique is used in everyday analytical chemistry, as well as its pros and cons
- Where MALDI-TOFMS is involved
- The types of molecules and samples MALDI-TOFMS is suitable for
- Where the technique is applicable, whether it be in academia or hospital environments
- When MALDI-TOFMS is the right choice
- Explore real-life case studies using MALDI-TOFMS in industries such as proteomics and complex organometallic analysis
- Interactive, exercises of example applications across clinical labs, life sciences, chemicals and energy sectors
What knowledge will I gain on Absolute Basics of MALDI-TOFMS?
This training is designed for anyone who needs an introduction to MALDI-TOFMS, including:
- For beginners to MALDI-TOFMS
- Analysts & technicians wanting a clear, structured refresher
- Laboratory or line managers overseeing MALDI-TOFMS instruments
- Data analysts and report writers who interpret results but do not use the instruments
- Service and consultant engineers who use MALDI-TOFMS
- Sales, marketing, or commercial teams working with MALDI-TOFMS systems, consumables, data or laboratory services
If MALDI-TOFMS touches your work in any way, this well-planned course delivered by experts in the field equips you to understand how to apply this to your everyday work.
Is this course for me?
By the end of the course, you will:
- Understand the principles and concepts of MALDI-TOFMS
- Know and define the key terminology associated with MALDI-TOFMS
- Feel confident discussing MALDI-TOFMS, sample preparation and workflows
- Understand what information MALDI-TOFMS provides when it comes to sample analysis
- Identify chemical concepts of MALDI-TOFMS from laser desorption ionisation to data acquisition
- Recognise how MALDI-TOFMS is used across diverse industries
This course gives you the language and understanding needed to use MALDI-TOFMS in everyday lab life.
Feedback from previous attendees
“The presenter was super knowledgeable. [Most useful topic:] The top tips for preparing a plate.” Sarah Hutchison, Team Leader, Scottish Water (July 2022).
“I enjoyed the show and tell aspects to explain some parts further and in practical terms; content was right level for absolute basics. The How MALDI-TOF works section was very interesting and forms a great foundation. July 2022.
“The many notes on the presentation. The videos and that the instructor showed the compartments on the live-stream.” July 2022.
