Applied ICP-MS interferences

Duration: 1 day for live courses
Experience level: Advanced
Delivery methods: Face-to-face | Offsite training & consultancy | Online | Onsite training & consultancy | Tailored training |
Type of course: Universal
Applicable to manufacturer(s):
CPD Approved: Not yet approved
Scheduled course price: £485.00 + TAX per delegate
Course discounts: RSC HEaTED Cambridge Network CAMS members receive a discount on this course

Your in-depth guide to inductively coupled plasma mass spectrometry (ICP-MS) interferences

This 1-day, classroom-based course offers an in depth level dive into inductively coupled plasma-mass spectrometry (ICP-MS) interferences, designed for those with basic to intermediate mass spectrometry knowledge.

This analytical chemistry training covers identifying and overcoming complex spectral and non-spectral interferences, including isobaric overlaps, polyatomic formations, and doubly charged ions, as well as physical transport effects.

This course will cover the theory and chemistry behind ICP-MS, plus it goes beyond how the instrumentation works to look into how various techniques and mitigations can be applied to an ICP-MS workflow in order to reduce interferences. Cement your knowledge by applying what you learn to real-life case studies involving ICP-MS interferences. Improve understanding further with the opportunity to handle and see (virtual courses) instrument parts such as an ICP torch, spray chamber and nebuliser.

Why should I join?

On completion of this ICP-MS training course you will have a more in-depth understanding of what causes interferences in ICP-MS how to spot them in data and mitigation techniques that can be applied to analysis and sample preparation.

This Applied ICP-MS interference course gives you:

A strong understanding ICP-MS interferences and the various types
Clear explanations of ICP-MS instrumentation and components
Understanding of the different types of interferences and the reasons behind them
Confidence to look at data and spot interferences
A good stepping stone, taking your basic knowledge of ICP-MS to a useful depth
A great refresher if you have not performed ICP-MS for a while

What would I learn?

This intermediate course focuses on the theory of ICP-MS and how the plasma and chemistry of samples can cause interferences during analysis.

The principles of inductively coupled plasma and mass spectrometry
Types of interference removal available and the method parameters that can be applied to enable this
Where interferences can occur in both ICP-MS and ICP-MS/MS
Uses of collision reaction cells (CRCs) to reduce polyatomic interferences
The use of cell gases in relation to interferences within the ICP-MS instrument
The reasons and uses of sample preparation techniques for ICP-MS
Polyatomic/isobaric interferences in ICP-MS and how CRC can be used to correct for this
Taking interferences into account during ICP-MS method development
Apply your knowledge to case-studies involving real-world data involving ICP-MS interference data across diverse industries including environmental monitoring for trace metals and the pharmaceutical industry

What knowledge will I gain?

By the end of the course, you will:

Understand the concepts of ICP-MS and why interferences occur
Have an insight into the types of interferences including polyatomic, isobaric and doubly charged interferences
Understand the ionisation and how fragmentation can lead to interferences
Comprehend the data produced by ICP-MS and what qualitative and quantitative information it can provide
Comprehend common interference removal strategies such as kinetic energy discrimination and matrix suppression
Recognise how sample preparation can be key to removing interferences in analysis
Understand how maintenance and troubleshooting can help reduce interferences in ICP-MS

Is this course for me?

This ICP-MS training course designed for anyone who would like an enhanced understanding of ICP-MS

Laboratory analysts & technicians using ICP-MS methods for elemental analysis
Laboratory or line managers overseeing ICP-MS instruments and analysis
Data analysts and report writers who work with ICP-MS data
Service engineers who want an in-depth view of ICP-MS as a technique
Sales, commercial or marketing teams who work with ICP-MS components, instruments, or services in anyway and would like more in-depth knowledge

If ICP-MS links to your work in anyway, this applied course delivered by experts in the field will provide you with a solid and deeper understanding of ICP-MS as an analytical technique.