TechTip 9: Installing a capillary column into a GC inlet/detector
Accurate capillary column positioning improves GC performance, minimizes contamination, and ensures reliable installation.
Tech tip
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TechTip 8: Know when a suspected problem really is a problem
Establish instrument and method baselines to quickly identify genuine problems and troubleshoot effectively.
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TechTip 7: Rotary pump maintenance – oil changes and use of the ballast valve
Understanding GC-MS spectral interpretation fundamentals improves compound identification beyond library search results.
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TechTip 6: Using press-fit capillary column connector
Proper press-fit connector installation prevents leaks, dead volumes, and thermal-lag related chromatographic issues.
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TechTip 5: When to replace a gas cylinder
Replace gas cylinders before depletion to prevent contamination, instrument damage, downtime, and reanalysis.
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TechTip 4: Random loss in sensitivity of injected samples through a GC batch
Systematic troubleshooting of samples, vials, syringes, leaks, and detectors resolves intermittent sensitivity losses.
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TechTip 3: GC splitless injections – how long until you open the split exit?
Correct splitless timing maximizes analyte transfer while minimizing solvent interference and peak distortion.
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TechTip 2: GC separation – standard column or more specialised?
Selecting the right GC column phase improves resolution, sensitivity, robustness, and method simplicity.
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TechTip 1: The power of sample introduction in GC and GC-MS
Optimized GC sample introduction parameters significantly improve transfer efficiency, selectivity, robustness, and performance.
