In this article on the Technology Networks website, Dr Diane Turner describes the technique of gas chromatography, how it works, how you read a chromatogram and the information it tells you, the strengths and limitations of gas chromatography and the common problems encountered. The article also describes taking gas chromatography into multiple dimensions through GC x GC.
Previous studies have indicated that volatile organic compounds specific to bladder cancer may exist in urine headspace, raising the possibility that they may be of diagnostic value for this particular cancer. To further examine this hypothesis, urine samples were collected from patients diagnosed with either bladder cancer or a non-cancerous urological disease/infection, and from healthy volunteers, from which the volatile metabolomes were analysed using gas chromatography mass spectrometry.
This paper evaluates the use of an on-site generated hydrogen carrier gas vs. helium as the carrier gas for USEPA Method 551.1, which analyses the concentration of pesticides in drinking water by liquid-liquid extraction followed by gas chromatography.